Woodruff School of Mechanical Engineering

NRE 8011/8012 and MP 6011/6012 Seminar

Nuclear & Radiological Engineering and Medical Physics Programs


Quantitative cone-beam CT imaging in radiation therapy using planning CT as a prior: framework design and first patient studies


Dr. Tianye Niu


Georgia Institute of Technology


Thursday, February 9, 2012 at 11:00:00 AM


Boggs Building, Room 3-47


Dr. Lei Zhu


Quantitative cone-beam CT (CBCT) imaging is on increasing demand for high-performance image guided radiation therapy (IGRT). However, the current CBCT has poor image qualities mainly due to scatter contamination. Its current clinical application is therefore limited to patient setup based on only bony structures. To improve CBCT imaging for quantitative use, we proposed a correction framework using planning CT (pCT) as the prior knowledge. The framework has been established using phantom studies on a tabletop CBCT system. More challenges arise in clinical implementations of our method, especially because patients have large organ deformation in different scans. To combat these challenges, we improve the framework to extend our research from bench to bedside by including several new components. In this presentation, we will introduce the framework design and demonstrate its promising performance using both phantom and patient results.


Tianye Niu joined the Nuclear & Radiological Engineering and Medical Physics Programs at Georgia Institute of Technology in October 2009. His research interests in the field of medical physics include two broad categories: improvement of the state-of-the-art medical imaging systems and development of next-generation imaging modalities for accurate disease diagnosis and treatment. Dr. Niu received his Ph.D. in physics electronics (2009) from the University of Science and Technology of China, Hefei, P.R.China.