Woodruff School of Mechanical Engineering
Faculty Candidate Seminar
Microfluidic and Nanomedicine Applications in Vascular Disease
Dr. Netanel Korin
Wyss Institute for Biologically Inspired Engineering, Harvard University
Thursday, March 28, 2013 at 11:00:00 AM
MRDC Building, Room 4211
The vascular system is a highly dynamic system that is tightly regulated under normal conditions. The interplay between hemodynamics, vascular physiology, and transport phenomena plays a key role in vascular disease. Micro- and nano- technologies offer unique opportunities for studying the biophysical determinants of vascular diseases as well as for utilizing these mechanisms to develop new diagnostic and therapeutic tools. This talk will present multidisciplinary efforts directed towards the development of biomedical micro- and nano- systems that could improve our understanding and treatment of vascular diseases. Two examples will be presented: 1) Shear activated nano-therapeutics for drug targeting to obstructed blood vessels. 2) Biomimetic microsystems for studying blood-tissue interaction in disease. These examples illustrate how integrating engineering principles with vascular physiology could be lead to the development of new strategies to address unmet clinical needs.
Netanel Korin is a Wyss Technology Development Fellow and a Research Associate in Don Ingberís group at the Wyss Institute for Biologically Inspired Engineering at Harvard University. He received a Bachelorís degree in Mechanical Engineering, a Masterís and a Ph.D. in Biomedical Engineering from the Technion Ė Israel Institute of Technology. Netanel has authored over 15 papers in Science, Nano letters, Lab on a Chip, Physical Review Letters, Journal of Biomechanics and other major research journals. His work has been highlighted in other leading journals including Nature, Nature Biotechnology, Nature Drug Discovery Reviews and New England Journal of Medicine. Netanel has also won several honors and awards including a Wyss Technology Development Fellowship, Outstanding Paper Award ASME NEMB, IEEE MNM best poster award, the International Society for Clinical Hemorheology (ISCH) Travel Award, and the Aaron and Miriam Gutwirth Memorial Scholarship. His research interests include vascular physiology, nano-biotechnology, microfluidics, hemodynamics and transport phenomena in biological systems.
Refreshments will be served.