Woodruff School of Mechanical Engineering

NRE/MP Seminar

Nuclear & Radiological Engineering and Medical Physics Programs


Development of GRID Minibeam Radiotherapy for Cancer Treatment


Mr. Greg and Serdar Szalkowski and Charyyev




Thursday, November 2, 2017 at 11:00:00 AM


Boggs Building, Room room 3-47


Chris Wang


Recently, many research groups worldwide have proposed the GRID radiation therapy (RT) using an array of submillimetric size beams (i.e. minibeams) of both synchrotron x-rays and protons to fully exploit the advantage of the volume effect of radiobiology. Specifically, the proposed beam width range from 0.5 to 1.0 mm. The notion was that the use of these submillimeter beam widths, which is about one order of magnitude smaller than the ones used in radiosurgery and in the conventional x-ray GRID RT, should show a sharp increase in healthy tissue tolerances. Since it has been shown that the tolerable dose increases sharply in rat spinal cord and in pig skin when the radiation field becomes smaller than approximately 4 mm, we believe that minibeams with approximately 3 mm in diameter should display much benefit of normal tissue sparing and that a beam size smaller than 3 mm is impractical considering the patient’s motion during a treatment. This talk will present some work at Georgia Tech on the development of such a minibeam using electrons, photons and protons.


Mr. Gregory Szalkowski and Mr. Serdar Charyyev are both PhD students at Georgia Tech with the focus on medical physics. Both are being advised by Dr. Chris Wang on their PhD theses. Mr. Szalkowski's thesis research is focused on the development of GRID minibeams of electrons and photons for cancer treatment. Mr. Charyyev's thesis research is focused on the development of proton GRID minibeams for cancer treatment.


Refreshments will be served.