Woodruff School of Mechanical Engineering

Faculty Candidate Seminar


Biologically Inspired Micro- and Nanofluidic Systems for Biomedical Applications


Dan Huh


Wyss Instutute, Harvard University, Boston, MA


Thursday, January 19, 2012 at 11:00:00 AM


MRDC Building, Room 4211


Dr. Levent Degertekin


Major advances in science and engineering have greatly enhanced our understanding of the fundamental principles that nature uses to build, control, and manipulate living systems. These insights into the inner workings of nature offer unique opportunities to develop new engineering principles inspired by biological systems and utilize them to create devices and materials that may potentially lead to transformative breakthroughs in biomedicine. This talk will present multidisciplinary efforts directed towards the development of biomedical micro- and nanofluidic systems inspired by the human body. Specifically, I will talk about i) a bioinspired microsystem that reproduces the key structure, dynamic mechanical activity, and complex organ-level functionality of the living human lung, ii) a microengineered model of human small airways and acoustically detectable cellular-level lung injury, and iii) tunable elastomeric nanochannels for nanofluidic manipulation of nanoparticles and DNA.


Dan Dongeun Huh received a Bachelorís degree in Mechanical Engineering from Seoul National University in 2000, Masterís degrees in Biomedical Engineering and Mechanical Engineering in 2002, and a Ph.D. in Biomedical Engineering from the University of Michigan in 2007. He then joined Don Ingber's group at Harvard Medical School and Children's Hospital Boston as a postdoctoral research fellow. Since 2009, he has been a Wyss Technology Development Fellow and a Research Associate at the Wyss Institute for Biologically Inspired Engineering at Harvard University. Dan has authored over 20 papers in Science, Nature, Nature Materials, PNAS, and other major research journals, and has won several honors and awards including a Finalist for INDEX: Design for Life Award, Scientific Breakthroughs of the Year from American Thoracic Society, Best Publication Award and Best Postdoctoral Award from the Society of Toxicology, Wyss Technology Development Fellowship from Harvard, Distinguished Achievement Award from Michigan, Widmer Award from microTAS, and Horace H. Rackham Predoctoral Fellowship. His research at the Wyss Institute focuses on developing bioinspired microsystems that mimic complex functionality of living human organs.