SUBJECT: Ph.D. Proposal Presentation
BY: Scott Schoen
TIME: Tuesday, November 26, 2019, 4:00 p.m.
PLACE: Engineered Biosystems Building (EBB), 3029
TITLE: Trans-skull Ultrasound for Imaging and Therapy
COMMITTEE: Dr. Costas D. Arvanitis, Chair (ME/BME)
Dr. Kenneth A. Cunefare (ME)
Dr. F. Levent Degertekin (ME)
Dr. Stanislav Emelianov (ECE/BME)
Dr. Karim G. Sabra (ME)


Ultrasound has emerged as a novel modality for the treatment and imaging of brain diseases. When enhanced by circulating microbubble agents, which scatter sound and vibrate in response to the incident ultrasound, it can enable a range of new therapeutic interventions and open new possibilities for imaging. Despite these advancements, the skull remains a major challenge both for therapy and imaging. This work proposes methods for fast, frequency-selective passive reconstruction of the acoustic field through human skull with applications including improved targeting for exploitation of nonlinear acoustic effects in the brain, controlling the microbubble dynamics, and super-resolution imaging.