|SUBJECT:||M.S. Thesis Presentation|
|TIME:||Friday, May 2, 2014, 11:00 a.m.|
|PLACE:||Love Building, 210|
|TITLE:||A Microfabricated Rapid Desalting Device with Integrated Electrospraying Tip|
|COMMITTEE:||Dr. Andrei Fedorov, Chair (ME)
Dr. Peter Kottke (ME)
Dr. Peter Hesketh (ME)
Electrospray Ionization (ESI) is a technique that permits the ionization of large proteins and biomolecules without fragmenting them, which allows them to be identified via Mass Spectrometry (MS). It has the potential of permitting the identification of transient intermediate products in biological processes in situ, which would provide great insight to researchers in the growing fields of proteomics and metabolomics. However, this application presents a technical challenge in that most relevant biochemistry occurs in aqueous solutions with high salt content, which makes successful identification of analytes by ESI-MS difficult.