|SUBJECT:||M.S. Thesis Presentation|
|TIME:||Tuesday, March 26, 2013, 9:00 a.m.|
|PLACE:||Molecular Science & Engineering Building, 3201 A|
|TITLE:||Design, Analysis, Testing, and Evaluation of a Prosthetic Venous Valve|
|COMMITTEE:||Dr. David Ku, Chair (ME)
Dr. Rudolph Gleason (ME)
Dr. Luke Brewster (Surgery)
Chronic Venous Insufficiency (CVI) is characterized by chronic venous hypertension, with venous reflux being a contributing factor in up to 94% of cases. The resulting symptoms include leg pain, varicose veins, fatigue, venous edema, skin pigmentation, inflammation, induration, and ulceration. A noninvasive treatment for deep venous reflux does not currently exist. A transcatheter prosthetic venous valve has the potential to be an effective, noninvasive treatment for deep venous reflux which could treat up to 1.4 million individuals in the United States suffering from venous ulceration and make more than 1.7 billion dollars each year. Previously developed prosthetic venous valves have had problems with competency, patency, thrombogenicity, biocompatibility, and incorrect sizing.