SUMMARY

Advances in miniaturization of electronics, multi-sensor integration, and low-power wireless communication have enabled new wearable devices for advanced human healthcare. Although there have been tremendous advancements and growth in the functionalities and market size of wearable electronics, there are still some limitations in their performance and user-friendliness that come from their rigidity, a fundamental mismatch with the soft, curvilinear nature of our skin. Recent advances in soft materials and system integration technologies have provided a unique opportunity to design various types of wearable flexible hybrid electronics (WFHE), or so-called Skintronics, for advanced human healthcare and human-machine interfaces. The hybrid integration of soft and biocompatible materials with miniaturized wireless wearable systems is undoubtedly an attractive prospect in the sense that successful device performance requires high degrees of mechanical flexibility, sensing capability, and user-friendly simplicity. This work focuses on studies of fabrication, material integration, mechanics, and overall device design to develop Skintronics for human healthcare. Demonstrations include fitness tracking, detection of blepharospasm (BSP) symptoms, and sleep health monitoring.