SUMMARY

Current wearable self-powered bioelectronics are inaccessible to a broader patient audience. The lack of sufficient self-rechargeable power sources and the wired communication infrastructure for bioelectronics become the main limitations. Human heat-dependent self-rechargeable systems face challenges because of the low power density of thermoelectric generators and the lack of sufficient electronics for effectively integrating these systems. The new thermoelectric materials, high throughput fabrication processes, and innovative thermoelectric design improve the power density of thermoelectric generators. This study improvises the fabrication of thermoelectric by utilizing high-throughput fabrication processes such as nano ink synthesis, screen printing, laser manufacturing, and flexible print circuit board in coordination to fabricate a wireless and well-integrated flexible thermoelectric-based bioelectronics system. Unlike conventional wired self-powered bioelectronics that limit portable health monitoring, this system harvests human body heat at a thermal gradient from 2K-10K in the ambient environment. Then, this energy powers the wireless bioelectronics at a low thermoelectric voltage of 30 mV. We demonstrate a successful clinical trial on a healthy human subject and gather good real-time physiological signals of electrocardiography (ECG) and electromyography (EMG). In conclusion, this study is the first successful application of measuring human physiological signals in a wireless charging environment, which paves the path for developing a self-sustainable, non-invasive wireless health monitoring system.